Kouamo Mangoua Mersimine is a PhD student at the University of Yaoundé 1, Cameroon carrying out research at CRID. Her research focuses on the role of guthation-s-transferase epsilon class in mosquito’s insecticide resistance. Her work with CRID started in 2018 under the LSTM Unit at OCEAC. Mersimine has been able to build experience in mosquito rearing, bioassay tests, evaluating the effectiveness of mosquito nets, DNA extraction, polymerase chain reaction, electrophoresis, quantitative PCR, mosquito’s injection, gene silencing, transgenic expression of detoxification genes on flies and proteins expression.
Under the supervision and collaboration of Principal Investigators, Mersimine has been able to publish the following papers:
1. A comparative evaluation of PBO-based and conventional bed nets using experimental huts reveals that glutathione-S transferase metabolic resistance is reducing the efficacy of PBO-based nets against the malaria vector Anopheles funestus in Cameroon
2. Polysaccharide fractions from Khaya grandifoliola stem bark and Cryptolepis sanguinolenta leaves: Partial characterization, Antioxidant and Immunomodulatory effects.
Mersimine is currently involved in a project titled “Functional validation of the role of An. funestus epsilon glutathione-s-transferases in insecticide resistance”